If the valves are proven to be capable of growing as the young lambs mature and age, Dr. Sodian then expects to begin offering transplantation of these heart valves into human babies who are born with heart valve defects, using autologous (in which the donor and recipient are the same person) stem cells derived from the umbilical cord blood of each newborn. From umbilical cord blood that was collected at the time of birth, cardiac surgeon Ralf Sodian and his colleagues in Munich were able to isolate those stem cells that are known to differentiate into cardiac tissue. These results sound dramatic, but are they an indication that we're getting close to perfecting this therapy? Copyright 2017 Neil H. Riordan, PA, PhD | All Rights Reserved, Medistem Panama – Adult Stem Cell Laboratory, Joe Rogan Interview with Mel Gibson and Dr. Riordan, Stem Cells: Their Role in Aging and in the Treatment of Chronic Diseases – Neil Riordan PA, PhD, Regenerative Medicine the Future of Interventional Orthopedics – Rudy Herrera, MD, Human Umbilical Cord Tissue-Derived Mesenchymal Stem Cells (hUC-MSCs) for Autism and Multiple Sclerosis – Christian Diaz MD, The Wild West of Stem Cells in the United States – Roberta Shapiro, DO, FAAPM&R, From Outside or Inside US Call: 1-954-358-3382, Joe Rogan and UFC Welterweight Champion Kamaru Usman Discuss Stem Cell Therapy in Panama and Dallas, Home Depot Founder Bernie Marcus Receives Stem Cell Therapy in Panama, The Neil Riordan Center for Regenerative Medicine Opens at Southwest College of Naturopathic Medicine & Health Sciences, Stem Cell Therapy for Autism – The Wonderful Story of Meadow and Summer. Stem cells derived from umbilical cord blood are known to be among the most versatile of all adult stem cells, having already been demonstrated to differentiate into a wide variety of tissue types, including cardiac tissue which is one of the most highly specialized and complex of all human bodily tissues since it is both muscular and electrical in nature. Each year thousands of babies in the U.S. alone are born with defective heart valves. Imagine you had a child with congenital heart disease and this child has to be operated on every 2 to 3 years. The basic idea is to implant something living, functional, from your own cells which will integrate into the surrounding tissue with the potential to grow. In extreme cases, when a valve cannot be surgically repaired, complete valve replacement is the only solution, although valves that are transplanted into babies and children typically do not grow over time as the child grows, thereby necessitating repeated operations throughout the individual’s life. Purchase a copy of Dr. Riordan’s new book about stem cell therapy today! Myocardial infarction is the leading cause of death worldwide. With valves that are too narrow or do not close completely with each beat of the heart, “regurgitation” of the blood can cause a number of systemic physiological problems, depending upon the severity of the defect. In what is known as a concept study, Dr. Sodian and his colleagues reported the results of their newly pioneered procedure today at the annual meeting of the American Heart Association in New Orleans. Currently, medical, pharmaceutical, and device-based therapies only delay the progression of the disease and do not actually repair the heart. If we replace a valve in a child, they will need surgery several times in their lifetime, because they will grow out of the device, so the ultimate goal is to have a construct which is able to grow with the child and only have to do the surgery once. Of all congenital heart defects, valve abnormalities are among the most common. We showed that it is possible to do this with human cells.”. As Dr. Sodian explains, “The problem is, if you have to do surgery on a child, you have a relatively small heart valve and the child grows out of it, which means you have to do the surgery many times. By Adam Pick on October 8, 2009. It’s very hard for children and parents. BISCA Tower 63rd FloorPanama City, Panama, Call Toll Free (US Only): 1-800-980-STEM (7836). The stem cells were then frozen and stored for 12 weeks, after which they were seeded and expanded upon a biodegradable polymer scaffold in the laboratory, from which eight new heart valves were grown.

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