The most effective intervention is early recognition and prompt treatment with topical steroid drops. A variant of the procedure, the mini-full-thickness corneal transplant, can be used to treat more focal defects in the cornea (Figure 3). There are a few types of endothelial keratoplasty. Rejection of the donor tissue is the most serious complication after a corneal transplant and occurs in 5 to 30 percent of patients. While long-term rejection data is not yet available for the newer endothelial corneal transplant procedures, lesser rejection rates have been demonstrated after Descemet Membrane Endothelial Keratoplasty (DMEK) (0.7%) and Descemet Stripping Automated Endothelial Keratoplasty (DSAEK) (9%) than full-thickness corneal transplant (17%) at 2 years in patients on the same postoperative steroid regimen and treated for similar indications 19). The surgeon will remove the diseased or damaged part of your cornea using a special instrument called a trephine. The 3 common causes that need surgery are keratoconus (where the surface of the cornea becomes cone-shaped, causing blurred vision), endothelial decompensation (where the cornea becomes swollen and cloudy), and scarring. Other If you have good vision in the non-transplant eye, you can legally drive 24 hours after surgery. If the endothelium of the graft makes contact with any surgical instruments, it will be damaged and the graft may fail; therefore, the surgical procedure is designed to avoid contacting the donor endothelium. Your entire cornea may need to be replaced if both the front and inner corneal layers are damaged. There is a higher risk of graft edge lifts compared with Descemet Stripping Automated Endothelial Keratoplasty (DSAEK), sometimes requiring a re-bubble procedure. Do not swim or lift anything heavy until you have checked with your surgeon. It’s held in place by an air bubble until a few days later, when it naturally sticks to the deep layer of the cornea. But in some patients it can progress to the point where a cornea transplant is necessary. The cornea is the ‘window of the eye’ – is the clear dome-shaped outer layer in front of your eye and the main focusing element. In some severe cases, cysts or bullae form on the surface of the eye which can cause sharp pain if they rupture. Ask your doctor which ones you can take. https://www.nei.nih.gov/, Eye Bank Association of America There is a higher risk of allograft rejection compared with other keratoplasty types. The devices are amenable for use in many situations in which other types of corneal transplant are not an option. Healing time after deep anterior lamellar keratoplasty (DALK) is shorter than after a full corneal transplant. He or she might be able to stop the rejection with medicine. When this happens, light does not focus normally on the retina, the layer at the back of the eye that is responsible for sight.

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