commonly associated with cytomegalovirus infection but also related to possible toxicities 13, Precision and Future Medicine, Vol. Marrow transplantation for acute nonlymphocytic leukemia after treatment with busulfan and cyclophosphamide. There are several complications which may occur during and even after a bone marrow transplant because this is a risky procedure. Stem cell or bone marrow transplants are complex treatments that carry a significant risk of serious complications. 2, 8 February 2000 | Bone Marrow Transplantation, Vol. Antimicrobial prophylaxis, modified chemotherapy and irradiation 6, Expert Opinion on Pharmacotherapy, Vol. A wide variety of pulmonary complications occur in bone marrow transplant (BMT) recipients and are a major cause of morbidity and death. 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Lung function after bone marrow grafting. 181, No. 1, 18 December 2012 | Insights into Imaging, Vol. 1, Clinical Microbiology and Infection, Vol. transplantation. 28, No. 11, No. 11, Clinical Nuclear Medicine, Vol. 17, No. Bone fragment emboli in the lungs of patients undergoing bone marrow transplantation. 7, 1 December 2000 | Radiology, Vol. 25, No. 29, No. Immature T lymphocytes in the peripheral blood of bone marrow transplant recipients. 3, Seminars in Roentgenology, Vol. 4, 18 August 2018 | Pediatric Radiology, Vol. often cause irreversible pulmonary disease, even in the patient who has had successful and mortality. Nosocomial Legionnaires' disease: occurrence in recipients of bone marrow transplants. 2, 12 July 2007 | Emergency Radiology, Vol. Treatment of cytomegalovirus pneumonia with high-dose acyclovir. Lymphocytic bronchitis associated with graft-versus-host disease in recipients of bone-marrow transplants. 3, Revista Clínica Española, Vol. 35, No. 1, The British Journal of Radiology, Vol. If CT findings are considered in relation to the time elapsed after BMT, diagnostic options can be narrowed sufficiently to enable accurate diagnosis. is hoped, minimize respiratory limitations. The exact mechanisms of lung injury are probably quite complex, and unfortunately, 2, The British Journal of Radiology, Vol. 94, No. Cytomegalovirus infections associated with leukocyte transfusions. 921, Journal of Thoracic Imaging, Vol. Alveolar macrophage dysfunction in human bone marrow transplant recipients. Pulmonary complications commonly occur during in selected persons. At CT, angioinvasive aspergillosis appears as a nodule surrounded by a halo of ground-glass attenuation; alveolar hemorrhage and drug reactions, as bilateral areas of ground-glass attenuation or consolidation; and pulmonary edema, as prominent pulmonary vessels, interlobar septal thickening, ground-glass attenuation, and pleural effusions. 9, Infectious Diseases in Clinical Practice, Vol. 2, Journal of Thoracic Imaging, Vol. Cyclosporin-A to prevent graft-versus-host disease: a pilot study in 22 patients receiving allogeneic marrow transplants. 10, No. 3, European Journal of Radiology, Vol. To read this article in full you will need to make a payment. The most frequent complication is called graft-versus-host disease (GvHD). Bone Marrow transplants for patients with nonmalignant diseases have a much better success rate with 70% to 90 % survival with a matched sibling donor and 36% to 65% with unrelated donors.The life expectancy, survival rate and quality of life post-transplant have improved with more accurate genetic matching with donors and improved post-operative care. Bone marrow transplantation for acute nonlymphoblastic leukaemia: a survey of the European Group for Bone Marrow Transplantation (EGBMT). 6, American Journal of Roentgenology, Vol. 1, Seminars in Roentgenology, Vol. High-dose chemotherapy directly destroys the bone marrow’s ability to produce white blood cells, red blood cells and platelets. By continuing you agree to the Use of Cookies. Fatal airway disease in an adult with chronic graftversus-host disease. 1, Diagnostic and Interventional Imaging, Vol. Rapidly progressive air-flow obstruction in marrow transplant recipients: possible association between obliterative bronchiolitis and chronic graft-versus-host disease. 5, No. 166, No. 1, Best Practice & Research Clinical Haematology, Vol. DOI: https://doi.org/10.1378/chest.87.2.237. Obstructive ventilation disorder as a severe complication of chronic graft-versus-host disease after bone-marrow transplantation. 19, No. The pulmonary toxicity of antineoplastic agents. 65, No. You may wish to discuss them with your treatment team and your family. 2, Journal of Thoracic Imaging, Vol. 3, American Journal of Roentgenology, Vol. Chronic graft-versus-host syndrome in man: a long-term clinicopathologic study of 20 Seattle patients. 29, No. Complications From Transplants Using Donor Stem Cells. 199, No. 15, No. 36, No. 1, American Journal of Roentgenology, Vol. 41, No. 1, European Journal of Radiology, Vol. 4, 23 May 2005 | Bone Marrow Transplantation, Vol. 1, European Journal of Radiology, Vol. 5, Journal of Thoracic Imaging, Vol. 3, Seminars in Roentgenology, Vol. Obstructive lung disease after allogeneic bone marrow transplantation. If the address matches an existing account you will receive an email with instructions to reset your password. 37, No. 48, No. From the Division of Thoracic Diseases and Internal Medicine, and the Division of Hematology and Internal Medicine, Mayo Clinic and Mayo Foundation, Rochester, MN.

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